What is Cycling AMP?
cyclic AMP and heart health & cardiovascular benefits
cyclic AMP levels in asthma treatment & bronchial health
Coleus extract has been found to have smooth muscle relaxant effect that results in bronchial tube dilation, decreasing airway resistance and increased lung air volume capacity. This action is the result of the increase in Cyclic AMP caused by coleus by inhibiting the enzymes that cause its breakdown. Increased cellular cyclic AMP likewise reduces histamine, making coleus beneficial in the treatment of allergy associated asthma.
Phytoextracts are natural products obtained from medicinal and aromatic plants (MAPs) that have been widely used for treating acute and chronic inflammation of lung [4,5]. Among them, thyme (Thymus vulgaris L.) is one of the most cited herbal remedies for the treatment of respiratory tract inflammations [6]. Thyme is an aromatic shrub of the Lamiaceae family occurring in the Mediterranean area where it is widely used either as flavouring of food and beverages or as herbal remedy for the treatment of respiratory and digestive disorders, parasitosis and urinary retention [7]. In particular, thyme is indicated, by traditional healers and physicians, as an antitussive, expectorant, antimicrobial and spasmolytic agent [8]. The Committee on Herbal Medicinal Products of the European Medicines Agency (EMA) has approved the use of thyme-based preparations, such as dry and liquid extracts and tinctures, for the treatment of cough associated with cold [9]. Furthermore, the German Commission E indicated thyme for treatments of cough, bronchitis and catarrh [8]. The pharmacological potential of thyme-based products is given by the presence of bioactive compounds such as phenolic monoterpenes (thymol), phenolic acids (rosmarinic and caffeic acid), flavonoids (rutin, luteolin, quercetin and apigenin derivatives), and triterpenes (ursolic and oleanolic acids). Moreover, thyme extract as other drugs (ex. guaifenesin) can be effective in reducing cellular content and secretion of MUC5AC, one of the components of mucus, being useful for the treatment of airway mucus hypersecretion. However, thyme extract effects in regulating cilia function have been never evaluated. Cilia beating frequency (CBF) is dramatically impaired in COPD and different pharmacological agents can modulate cilia function. Indeed, CBF is dependent on the soluble nucleotides cAMP and cGMP and intracellular calcium concentrations [15,16]. Since the rate of cAMP efflux is proportional to the intracellular levels of cAMP and the process begins within minutes following stimulation of adenylyl cyclase.
role of cyclic AMP in blood vessel relaxation & vasodilation
medicinal plants that increase cyclic AMP
Green Tea Extract and cyclic AMP levels
natural ways to increase cyclic AMP
- increase cyclic AMP naturally
- natural cyclic AMP boosters
- herbs to increase cyclic AMP
- natural methods for cyclic AMP elevation
12 natural products and herbs that stimulate cAMP production:
| No. | Natural Product/Herb | Description |
|---|---|---|
| 1 | Forskolin | An active compound derived from the roots of the Coleus forskohlii plant, traditionally used in Ayurvedic medicine. |
| 2 | Caffeine | A central nervous system stimulant found in coffee, tea, and other beverages. |
| 3 | Green Tea Extract | Contains catechins which may help raise cAMP levels. |
| 4 | Yohimbine | Derived from the bark of the yohimbe tree, often used to support fat loss. |
| 5 | Ginkgo Biloba | An ancient plant extract used in traditional medicine to treat blood disorders and improve memory. |
| 6 | Ginseng | Often used in traditional medicine for its adaptogenic properties. |
| 7 | Ephedrine | Derived from the plant Ephedra sinica, it is often used for weight loss and as a decongestant. |
| 8 | Artichoke Extract | Believed to increase cAMP by inhibiting phosphodiesterase. |
| 9 | Bitter Orange | Used in traditional medicine as a stimulant and appetite suppressant. |
| 10 | Quercetin | A plant flavonoid that has antioxidant properties. |
| 11 | Resveratrol | A polyphenol found in grapes, blueberries, and other fruits with antioxidant effects. |
| 12 | Astragalus | Used in traditional Chinese medicine, believed to increase cAMP levels. |
cyclic AMP related research studies: https://www.sciencedirect.com/science/article/abs/pii/S0753332218323072
